1-Bromobutane

1-Bromobutane

SCHEMBL9495841

CCCCBr.O=P(O)(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of 1-Bromobutane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.46
LPAR2 Q9HBW0 3/20 0.46
FDPS P14324 11/20 0.44
GGPS1 O95749 3/20 0.41
LPAR1 Q92633 2/20 0.41
GABBR2 O75899 1/20 0.41
GABRR1 P24046 1/20 0.41
GABBR1 Q9UBS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Bromobutane SCHEMBL21328523 0.97 LPAR3 (0.44) LPAR3LPAR2FDPSGGPS1LPAR1
Phosphoric Acid SCHEMBL29208287 0.89 LPAR3 (0.54) LPAR3LPAR2FDPSGGPS1LPAR1
Phosphoric Acid SCHEMBL9499749 0.84
Pentane SCHEMBL3133026 0.81 LPAR3 (0.55) LPAR3LPAR2FDPSGGPS1LPAR1
Hexane SCHEMBL18769800 0.81 LPAR3 (0.63) LPAR3LPAR2FDPSGGPS1LPAR1
Hexane SCHEMBL27668811 0.81 LPAR3 (0.63) LPAR3LPAR2FDPSGGPS1LPAR1
Pentane SCHEMBL4312559 0.81 LPAR3 (0.55) LPAR3LPAR2FDPSGGPS1LPAR1
Hexane SCHEMBL6862689 0.81 LPAR3 (0.63) LPAR3LPAR2FDPSGGPS1LPAR1
1-Bromobutane SCHEMBL15864737 0.80
1-Bromobutane SCHEMBL8141 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117987140-A Composite fluorescent material, preparation method thereof and perovskite-based composite light conversion film 兰州大学 2024-05-07 CN claimed
CN-117987140-A Composite fluorescent material, preparation method thereof and perovskite-based composite light conversion film 兰州大学 2024-05-07 CN disclosed
EP-0229014-B1 MAGNETIC RECORDING MEDIUM SONY CORPORATION (JP) 1993-03-24 EP disclosed
US-4735848-A PERFLUOROALKYL ESTER LUBRICANT SONY CORPORATION (JP) 1988-04-05 US disclosed
EP-0229014-A2 Magnetic recording medium SONY CORPORATION (JP) 1987-07-15 EP disclosed