Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563905 | 0.99 | RARB (0.50) | PTPN11NR5A1RARBNPC1RAB9A | |
| SCHEMBL26044944 | 0.95 | LMNA (0.47) | PTPN11RARBNPC1RAB9AMEN1 | |
| SCHEMBL9494660 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9493546 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9493501 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9494594 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9494586 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9496980 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9494141 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 | |
| SCHEMBL9494088 | 0.92 | NR5A1 (0.56) | PTPN11NR5A1RARBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |