Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzoyl Peroxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | F2 | P00734 | 1/20 | 0.94 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Peroxide SCHEMBL28263485 | 1.00 | LMNA (0.94) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL63 | 0.97 | LMNA (1.00) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL2929886 | 0.97 | LMNA (1.00) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL5312311 | 0.97 | LMNA (1.00) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL3467853 | 0.97 | LMNA (1.00) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL9407293 | 0.97 | LMNA (1.00) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL7546726 | 0.94 | LMNA (0.94) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL11134661 | 0.94 | LMNA (0.94) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL4745654 | 0.94 | LMNA (0.94) | LMNAF2TSHRALDH1A1TDP1 | |
| Benzoyl Peroxide SCHEMBL178097 | 0.94 | LMNA (0.94) | LMNAF2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995710-A | Inorganic silicon modified soap-free acrylic emulsion and preparation method thereof | 罗良胜 | 2020-11-27 | — | — | CN | claimed |
| CN-113924144-A | Isopropyl carbonate benzoyl peroxide composition and using method thereof | 高德美控股有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-111995710-A | Inorganic silicon modified soap-free acrylic emulsion and preparation method thereof | 罗良胜 | 2020-11-27 | — | — | CN | disclosed |
| CN-109467638-B | zero-VOC, polyester-modified hydroxyacrylic acid dispersions and process for their preparation | 无锡洪汇新材料科技股份有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-1094497-C | Nanometre inorganic particle toughened reinforced plastics and preparation method thereof | UNIV ZHONGSHAN (CN) | 2002-11-20 | — | — | CN | disclosed |
| CN-1228443-A | Nanometre inorganic particle toughened reinforced plastics and preparation method thereof | UNIV ZHONGSHAN (CN) | 1999-09-15 | — | — | CN | disclosed |
| EP-0279311-B1 | THE USE OF BINDER COMBINATIONS IN SOLVENT CONTAINING COATINGS FOR PARTS OF MOTOR VEHICLES | BAYER AG (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0279311-A2 | The use of binder combinations in solvent containing coatings for parts of motor vehicles | BAYER AG (DE) | 1988-08-24 | — | — | EP | disclosed |
| EP-0170930-B1 | CURABLE POLYMER RESINS AND THEIR USE AS BINDING AGENTS IN COATINGS | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |
| EP-0210429-A2 | Vehicle combinations for synthetic resin painting | BAYER AG (DE) | 1987-02-04 | — | — | EP | disclosed |
| US-4639499-A | UNSATURATED DIOL, CAPROLACTONE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0170930-A1 | Curable polymer resins and their use as binding agents in coatings | BAYER AG (DE) | 1986-02-12 | — | — | EP | disclosed |