Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496931 | 1.00 | GAA (0.42) | GAASIRT2CYP19A1 | |
| SCHEMBL14677339 | 0.87 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL22033434 | 0.85 | SIRT2 (0.46) | GAASIRT2CYP19A1 | |
| SCHEMBL4813024 | 0.71 | SIRT2 (0.42) | SIRT2CYP19A1 | |
| SCHEMBL11534270 | 0.68 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL7408970 | 0.67 | — | — | |
| SCHEMBL6077915 | 0.67 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL3201760 | 0.66 | CYP19A1 (0.48) | CYP19A1 | |
| Hexadecane SCHEMBL28112342 | 0.65 | CRBN (0.58) | CYP19A1 | |
| Dodecane SCHEMBL27509294 | 0.65 | CRBN (0.58) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208223-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5144045-A | Treatment of inflammatory related disorders | AMERICAN CYANAMID COMPANY (US) | 1992-09-01 | — | — | US | disclosed |