SCHEMBL9497432

SCHEMBL9497432

CCC1CCC(C#Cc2ccc(F)cc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.42
FFAR4 Q5NUL3 2/20 0.37
PAX8 Q06710 3/20 0.35
GRIN2B Q13224 1/20 0.35
ACACB O00763 1/20 0.33
P2RY6 Q15077 1/20 0.32
APP P05067 1/20 0.32
GRM5 P41594 1/20 0.32
HAO1 Q9UJM8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497422 1.00 FFAR1 (0.42) FFAR1FFAR4PAX8GRIN2BACACB
SCHEMBL9243857 0.95 FFAR1 (0.39) FFAR1FFAR4PAX8GRIN2BACACB
SCHEMBL9243863 0.95 FFAR1 (0.39) FFAR1FFAR4PAX8GRIN2BACACB
SCHEMBL9496202 0.91 FFAR1 (0.47) FFAR1FFAR4ACACBP2RY6APP
SCHEMBL9854903 0.91 FFAR1 (0.47) FFAR1FFAR4ACACBP2RY6APP
SCHEMBL9500386 0.87 FFAR1 (0.40) FFAR1FFAR4PAX8GRIN2BP2RY6
SCHEMBL9500394 0.87 FFAR1 (0.40) FFAR1FFAR4PAX8GRIN2BP2RY6
SCHEMBL9496660 0.84 FFAR1 (0.38) FFAR1FFAR4PAX8P2RY6
SCHEMBL9496653 0.84 FFAR1 (0.38) FFAR1FFAR4PAX8P2RY6
SCHEMBL9498083 0.83 FFAR1 (0.42) FFAR1FFAR4ACACBGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306505-B1 ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES MERCK PATENT GmbH (DE) 1993-03-24 EP disclosed
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed