Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496202 | 1.00 | FFAR1 (0.47) | FFAR1FFAR4ACACBHAO1KCNH2 | |
| SCHEMBL9497422 | 0.91 | FFAR1 (0.42) | FFAR1FFAR4ACACBHAO1P2RY6 | |
| SCHEMBL9497432 | 0.91 | FFAR1 (0.42) | FFAR1FFAR4ACACBHAO1P2RY6 | |
| SCHEMBL9498077 | 0.91 | FFAR1 (0.42) | FFAR1FFAR4ACACBKCNH2PGK1 | |
| SCHEMBL9498083 | 0.91 | FFAR1 (0.42) | FFAR1FFAR4ACACBKCNH2PGK1 | |
| Fluoride SCHEMBL9841456 | 0.90 | FFAR1 (0.41) | FFAR1FFAR4ACACBHAO1PTGES | |
| SCHEMBL8775478 | 0.90 | FFAR1 (0.48) | FFAR1FFAR4ACACBKCNH2PTGES | |
| SCHEMBL9495017 | 0.87 | FFAR1 (0.39) | FFAR1FFAR4CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL8775279 | 0.87 | FFAR1 (0.52) | FFAR1FFAR4ACACBPTGESPGK1 | |
| SCHEMBL9855349 | 0.87 | FFAR1 (0.39) | FFAR1FFAR4CHRNB2CHRNA2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |