Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778843 | 0.87 | ADRB2 (0.36) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL9497176 | 0.87 | CYP3A4 (0.37) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL14779273 | 0.85 | ADRB2 (0.35) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL8357514 | 0.85 | ADRB2 (0.35) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL14778424 | 0.83 | TSHR (0.36) | ADRB2ADRB1ADRB3TSHRTHRB | |
| SCHEMBL14779006 | 0.83 | TSHR (0.36) | ADRB2ADRB1ADRB3TSHRTHRB | |
| SCHEMBL14779199 | 0.83 | TSHR (0.36) | ADRB2ADRB1ADRB3TSHRTHRB | |
| SCHEMBL14778560 | 0.83 | TSHR (0.36) | ADRB2ADRB1ADRB3TSHRTHRB | |
| SCHEMBL9497034 | 0.81 | — | — | |
| SCHEMBL14779460 | 0.80 | CYP3A4 (0.40) | ADRB2ADRB1ADRB3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072648-A1 | SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-21 | — | — | US | disclosed |
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |