Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL30418124 | 0.96 | FFAR3 (0.53) | — | |
| Propionic Acid SCHEMBL240639 | 0.96 | FFAR3 (0.53) | — | |
| Propionic Acid SCHEMBL15821499 | 0.92 | — | — | |
| Propionic Acid SCHEMBL11788756 | 0.92 | FFAR3 (0.50) | — | |
| Propionic Acid SCHEMBL7719958 | 0.92 | FFAR3 (0.50) | — | |
| Propionic Acid SCHEMBL15820339 | 0.92 | FFAR3 (0.50) | — | |
| Propionic Acid SCHEMBL11421578 | 0.92 | — | — | |
| Propionic Acid SCHEMBL15821252 | 0.92 | — | — | |
| Propionic Acid SCHEMBL15820832 | 0.92 | FFAR3 (0.50) | — | |
| Propionic Acid SCHEMBL1118869 | 0.92 | FFAR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107967-B2 | CATALYST COMPOSITION FOR USE IN THE POLYMERIZATION OR COPOLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0107967-B1 | CATALYST COMPOSITION FOR USE IN THE POLYMERIZATION OR COPOLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-4525469-A | TITANIUM COMPONENT AND ORGANOALUMINUM COMPONENT | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0107967-A1 | Catalyst composition for use in the polymerization or copolymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |