SCHEMBL9497969

SCHEMBL9497969

CC(C)(OO)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
ALOX15 P16050 2/20 0.62
ESR1 P03372 11/20 0.56
ESR2 Q92731 10/20 0.56
CYP3A4 P08684 4/20 0.56
LMNA P02545 2/20 0.56
TYR P14679 2/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
AR P10275 1/20 0.56
TSHR P16473 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
HTR6 P50406 1/20 0.56
ESRRG P62508 1/20 0.56
SLC6A3 Q01959 1/20 0.56
SHBG P04278 1/20 0.46
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5943678 0.89 ALDH1A1 (0.75) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL11811353 0.82 ALDH1A1 (0.65) ALDH1A1ALOX15LMNATYRHPGD
SCHEMBL9175386 0.82 ALDH1A1 (0.65) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL11700789 0.80 ESR1 (0.56) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL5545791 0.80 ALDH1A1 (0.62) ALDH1A1ALOX15LMNATYRTSHR
SCHEMBL8578305 0.80 ALDH1A1 (0.62) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL8983667 0.80 ALDH1A1 (0.62) ALDH1A1ALOX15CYP3A4LMNATSHR
SCHEMBL10618279 0.78 ALDH1A1 (0.60) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL28329682 0.78 ALDH1A1 (0.60) ALDH1A1ALOX15CYP3A4HPGDHSD17B10
SCHEMBL9342853 0.78 ALDH1A1 (0.54) ALDH1A1ALOX15ESR1ESR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423185-B Method for selectively oxidizing cumene compound 浙江工业大学 2022-03-18 CN disclosed
CN-110423185-A Method for selectively oxidizing cumene compound UNIV ZHEJIANG TECHNOLOGY 2019-11-08 CN disclosed
EP-0327361-B1 3-(2-HYDROPEROXY-2-PROPYL)PHENOL AND METHOD OF PRODUCING RESORCINOL USING THE SAME MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-17 EP disclosed
US-5068455-A Oxidation of 3-(2-hydroxy-2-propyl)phenol or m-isopropenylphenol to form hydroperoxide MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-26 US disclosed
US-5030767-A Decomposition, solvent, inorganic acid or arenesulfonic acid as catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-09 US disclosed
EP-0327361-A1 3-(2-hydroperoxy-2-propyl)phenol and method of producing resorcinol using the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-09 EP disclosed
US-4695658-A Aryl carboxylate process FMC CORPORATION (US) 1987-09-22 US disclosed