Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390181 | 0.90 | — | — | |
| SCHEMBL8851974 | 0.85 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL30438020 | 0.83 | GAA (0.57) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12643965 | 0.83 | — | — | |
| SCHEMBL3895519 | 0.81 | — | — | |
| SCHEMBL5932605 | 0.79 | NAAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10051077 | 0.79 | — | — | |
| SCHEMBL15496396 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9380573 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9126787 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135084-A2 | Tetrahydroisoquinolincarbamic-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1985-03-27 | — | — | EP | claimed |
| EP-2315768-B1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2017-08-09 | — | — | EP | disclosed |
| EP-2240494-B1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-30 | — | — | EP | disclosed |
| US-8637491-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA S.A. (BE) | 2014-01-28 | — | — | US | disclosed |
| US-8487101-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA S.A. (BE) | 2013-07-16 | — | — | US | disclosed |
| US-20110172191-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2011-07-14 | — | — | US | disclosed |
| EP-2315768-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB Pharma, S.A. (BE) | 2011-05-04 | — | — | EP | disclosed |
| US-20110021558-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2011-01-27 | — | — | US | disclosed |
| EP-2240494-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB Pharma, S.A. (BE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009153554-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-12-23 | — | — | WO | disclosed |
| EP-0558076-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| EP-0528435-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5393648-A | Dispersion of hydrophobic compound dye and polymer; dye is inactuve during storage, but readily decolored and eluted i in processing | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-28 | — | — | US | disclosed |
| US-5391470-A | Dispersion of hydrophobic compound and water-insoluble, organic solvent-soluble polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5328818-A | Support with color couplers in emulsions in multilayer element | FUJI PHOTO FILM CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5288600-A | Containing water insoluble, solvent solubility polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| US-5264333-A | Multilayer element with emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0558076-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| EP-0528435-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| EP-0135084-A2 | Tetrahydroisoquinolincarbamic-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172191-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | MAP2K2, MAP2K1, MAP2K3 | GAA 4428/4885MGAM 3422/4885SI 4271/4885 |
| US-20110021558-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | MAP3K6, MAPK1, MAP3K20 | GAA 4229/4885MGAM 3602/4885SI 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.