Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.66 |
| ▸ | CNR2 | P34972 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498573 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9446331 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9446334 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9498071 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9857301 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL9858218 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL9857303 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL10716137 | 0.95 | CNR1 (0.59) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9497942 | 0.92 | KDM4E (0.64) | CNR1TP53CYP3A4MAPTKDM4E | |
| SCHEMBL9498652 | 0.92 | KDM4E (0.64) | CNR1TP53CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283742-B1 | FATTY ACID AMIDES AS INHIBITORS OF ACYL-COA: CHOLESTEROL ACYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1993-05-26 | — | — | EP | claimed |
| EP-0283742-A2 | Fatty acid amides as inhibitors of acyl-CoA: cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0283742-B1 | FATTY ACID AMIDES AS INHIBITORS OF ACYL-COA: CHOLESTEROL ACYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| EP-0283742-A2 | Fatty acid amides as inhibitors of acyl-CoA: cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |