Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.66 |
| ▸ | CNR2 | P34972 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498564 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9498573 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9446334 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9498071 | 1.00 | CNR1 (0.66) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9857301 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL9858218 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL9857303 | 0.98 | CNR1 (0.63) | CNR1CNR2EPHX2FAAH | |
| SCHEMBL10716137 | 0.95 | CNR1 (0.59) | CNR1CNR2TP53CYP3A4MAPT | |
| SCHEMBL9497942 | 0.92 | KDM4E (0.64) | CNR1TP53CYP3A4MAPTKDM4E | |
| SCHEMBL9498652 | 0.92 | KDM4E (0.64) | CNR1TP53CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295637-B1 | LIPID REGULATING COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| US-4859703-A | Lipid regulating compositions | WARNER-LAMBERT COMPANY (US) | 1989-08-22 | — | — | US | claimed |
| US-4751026-A | INHIBITING INTESTINAL ABSORPTION OF CHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1988-06-14 | — | — | US | claimed |
| EP-0242610-A1 | Substituted anilides of oleic, linoleic or linolenic acid as inhibitors of acyl-coa: cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1987-10-28 | — | — | EP | claimed |
| US-20090182014-A1 | INSECTICIDAL COMPOSITIONS COMPRISING COMPOUNDS HAVING INHIBITORY ACTIVITY VERSUS ACYL COA: CHOLESTEROL ACYLTRANSFERASE OR SALTS THEREOF AS EFFECTIVE INGREDIENTS | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-07-16 | — | — | US | disclosed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |
| EP-0295637-B1 | LIPID REGULATING COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4859703-A | Lipid regulating compositions | WARNER-LAMBERT COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0295637-A2 | Lipid regulating compositions | WARNER-LAMBERT COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4751026-A | INHIBITING INTESTINAL ABSORPTION OF CHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0242610-A1 | Substituted anilides of oleic, linoleic or linolenic acid as inhibitors of acyl-coa: cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182014-A1 | INSECTICIDAL COMPOSITIONS COMPRISING COMPOUNDS HAVING INHIBITORY ACTIVITY VERSUS ACYL COA: CHOLESTEROL ACYLTRANSFERASE OR SALTS THEREOF AS EFFECTIVE INGREDIENTS | ACAT2, LCAT, ACAT1 | CNR1 2456/4885CNR2 2537/4885TP53 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.