SCHEMBL9498596

SCHEMBL9498596

Oc1ccc(CC(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.60
ESR2 Q92731 5/20 0.60
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
TRPV1 Q8NER1 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
SLC7A5 Q01650 1/20 0.46
TAAR1 Q96RJ0 2/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27564167 0.94 ESR1 (0.62) ESR1ESR2MTNR1AMTNR1BFNTA
SCHEMBL6744903 0.87 ESR1 (0.76) ESR1ESR2TAAR1SLC6A2
SCHEMBL146771 0.87 MTNR1A (0.55) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL15903897 0.86 ESR1 (0.55) ESR1ESR2SLC7A5TAAR1SLC6A2
SCHEMBL27833227 0.86 ESR1 (0.82) ESR1ESR2MTNR1AMTNR1BTAAR1
SCHEMBL28638808 0.84 ESR1 (0.54) ESR1ESR2TRPV1SIGMAR1
SCHEMBL28696042 0.84 MTNR1A (0.53) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
Hydrochloric Acid SCHEMBL30185866 0.84 MTNR1A (0.53) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL15288808 0.84 ESR1 (0.56) ESR1ESR2MTNR1AMTNR1BFNTA
SCHEMBL15288809 0.84 ESR1 (0.56) ESR1ESR2MTNR1AMTNR1BFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310973-B1 LEVELLING AGENT BAYER AG (DE) 1993-05-12 EP disclosed
US-4943299-A HIGH TEMPERATURE DYEING BAYER AKTIENGESELLSCHAFT (DE) 1990-07-24 US disclosed
EP-0310973-A2 Levelling agent BAYER AG (DE) 1989-04-12 EP disclosed