Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497041 | 0.85 | GMNN (0.45) | USP2PLA2G2CHTTCES2GMNN | |
| SCHEMBL31135395 | 0.75 | CES2 (0.46) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL7797300 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11734142 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11739224 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11580000 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11735424 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11734597 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11580806 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB | |
| SCHEMBL11738017 | 0.75 | USP2 (0.61) | USP2PLA2G2CHTTMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208223-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5144045-A | Treatment of inflammatory related disorders | AMERICAN CYANAMID COMPANY (US) | 1992-09-01 | — | — | US | disclosed |