Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 15/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046348 | 0.90 | CA2 (0.51) | TTRAPEX1NSD2CA2 | |
| SCHEMBL27522317 | 0.82 | CA2 (0.50) | TTRAPEX1CA2ALDH1A1HSD17B10 | |
| SCHEMBL11426051 | 0.82 | APEX1 (0.49) | TTRAPEX1NSD2CA2TDP1 | |
| SCHEMBL635315 | 0.82 | CA2 (0.57) | TTRAPEX1CA2 | |
| SCHEMBL9178147 | 0.81 | TTR (0.58) | TTRAPEX1NSD2ALDH1A1CYP3A4 | |
| SCHEMBL11682682 | 0.81 | TTR (0.50) | TTRAPEX1NSD2CA2ALDH1A1 | |
| SCHEMBL1861706 | 0.79 | CA2 (0.59) | APEX1NSD2CA2TSHRHSD17B10 | |
| Sulfuric Acid SCHEMBL27866658 | 0.79 | CA2 (0.54) | TTRAPEX1CA2 | |
| SCHEMBL9097803 | 0.79 | CA1 (0.53) | APEX1CA2ALDH1A1CYP3A4TSHR | |
| SCHEMBL30804445 | 0.76 | TTR (1.00) | TTRNSD2ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384265-B1 | PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0384265-A1 | Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4948917-A | REACTING PHOSGENE AND BETA-HYDROXYETHYLSULFONYL-ARYLAMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| US-4745187-A | Process for the preparation of water-soluble phthalocyanine dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |