Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450545 | 0.82 | SOAT1 (0.42) | SOAT1 | |
| SCHEMBL4924571 | 0.78 | CYP19A1 (0.41) | SOAT1 | |
| SCHEMBL4914943 | 0.76 | — | — | |
| SCHEMBL29611988 | 0.72 | NR5A1 (0.52) | — | |
| SCHEMBL10628797 | 0.69 | KDM4E (0.47) | — | |
| SCHEMBL4618500 | 0.68 | — | — | |
| SCHEMBL28601360 | 0.68 | KCNA3 (0.55) | HRH3 | |
| SCHEMBL4977384 | 0.67 | LMNA (0.53) | — | |
| SCHEMBL29612130 | 0.65 | NR5A1 (0.56) | — | |
| SCHEMBL29611696 | 0.65 | NR5A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532634-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018879-A1 | PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |