Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368675 | 0.88 | AR (0.43) | SLC22A12ARRORCUBE2MDCUN1D1 | |
| SCHEMBL9501405 | 0.82 | KMT2A (0.41) | AREPHX2 | |
| SCHEMBL9500262 | 0.81 | HIF1A (0.43) | SLC22A12ARHIF1APLA2G7LMNA | |
| SCHEMBL9503090 | 0.81 | SLC22A12 (0.43) | SLC22A12ARRORCHIF1AHPGD | |
| SCHEMBL9499366 | 0.81 | SLC22A12 (0.53) | SLC22A12RORCHIF1AIDH1LMNA | |
| SCHEMBL9500825 | 0.80 | SLC22A12 (0.45) | SLC22A12ARRORCBRAFKCNN4 | |
| SCHEMBL9368636 | 0.78 | SLC22A12 (0.41) | SLC22A12ARRORCHIF1AHPGD | |
| SCHEMBL9363640 | 0.78 | SLC22A12 (0.43) | SLC22A12ARRORCKCNN4PLA2G7 | |
| SCHEMBL9363435 | 0.77 | SLC22A12 (0.45) | SLC22A12ARRORCTP53GRM4 | |
| SCHEMBL9363483 | 0.75 | SLC22A12 (0.44) | SLC22A12ARTP53GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |