Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499503 | 1.00 | FFAR1 (0.50) | FFAR1FFAR4ACACBTSHRHSD17B10 | |
| SCHEMBL8775279 | 0.94 | FFAR1 (0.52) | FFAR1FFAR4ACACBMAOAMAOB | |
| SCHEMBL9495021 | 0.92 | FFAR1 (0.48) | FFAR1FFAR4ACACBTSHRHSD17B10 | |
| SCHEMBL9495028 | 0.92 | FFAR1 (0.48) | FFAR1FFAR4ACACBTSHRHSD17B10 | |
| SCHEMBL9497026 | 0.91 | FFAR1 (0.50) | FFAR1FFAR4ACACBMAOAMAOB | |
| SCHEMBL9497038 | 0.91 | FFAR1 (0.50) | FFAR1FFAR4ACACBMAOAMAOB | |
| SCHEMBL9497050 | 0.91 | FFAR1 (0.50) | FFAR1FFAR4ACACBMAOAMAOB | |
| SCHEMBL9494848 | 0.91 | HSD17B10 (0.50) | FFAR1FFAR4TSHRHSD17B10HRH3 | |
| SCHEMBL9494844 | 0.91 | HSD17B10 (0.50) | FFAR1FFAR4TSHRHSD17B10HRH3 | |
| SCHEMBL9497001 | 0.90 | FFAR1 (0.49) | FFAR1FFAR4ACACBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |