SCHEMBL9499547

SCHEMBL9499547

CCCCCOc1ccc(C#CC2CCC(C3CCC(CC)CC3)CC2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9495322 1.00 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL9855548 1.00 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL9854915 0.97
SCHEMBL9494902 0.97
SCHEMBL9494894 0.97
SCHEMBL9500098 0.97 ALDH1A1 (0.34) ALDH1A1HPGD
SCHEMBL9500089 0.97 ALDH1A1 (0.34) ALDH1A1HPGD
SCHEMBL9496463 0.95 ALDH1A1 (0.36) ALDH1A1HPGD
SCHEMBL9496457 0.95 ALDH1A1 (0.36) ALDH1A1HPGD
SCHEMBL9498031 0.93 HTR2C (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306505-B1 ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES MERCK PATENT GmbH (DE) 1993-03-24 EP disclosed
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed