Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413226 | 0.88 | ALDH1A1 (0.33) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL1413138 | 0.73 | AURKA (0.39) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL11595998 | 0.72 | AURKA (0.51) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL1413164 | 0.71 | NT5E (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL7894720 | 0.70 | AURKB (0.38) | ALDH1A1HSD17B10AURKAAURKB | |
| SCHEMBL1413136 | 0.69 | — | — | |
| SCHEMBL6632032 | 0.67 | AURKA (0.45) | TDP1AURKAAURKB | |
| SCHEMBL11340204 | 0.67 | NT5E (0.45) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4409480 | 0.67 | TTR (0.37) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL5033149 | 0.64 | TTR (0.43) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344343-B1 | PROCESS FOR THE REGIOSPECIFIC SULFONATION OF 2-AMINO-NAPHTALENES SUBSTITUTED IN THE 5- OR 7-POSITION BY A FIBRE REACTIVE VS-GROUP, THE NOVEL 5-SULFO-SUBSTITUTED FIBER-REACTIVE 2-AMINO-NAPHTHALENE, AND FIBRE-REACTIVE AZO DYES THEREOF | HOECHST CELANESE CORPORATION (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0344343-A1 | Process for the regiospecific sulfonation of 2-amino-naphtalenes substituted in the 5- or 7-position by a fibre reactive vs-group, the novel 5-sulfo-substituted fiber-reactive 2-amino-naphthalene, and fibre-reactive azo dyes thereof | HOECHST CELANESE CORPORATION (US) | 1989-12-06 | — | — | EP | claimed |