Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760552 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| Hydrochloric Acid SCHEMBL9759792 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL11049649 | 0.87 | MAPT (0.59) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL11045778 | 0.86 | GLA (0.42) | SMN1; SMN2MAPTLMNAKMT2ANPC1 | |
| SCHEMBL10577117 | 0.83 | GLA (0.43) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL21315653 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL29961863 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL10580319 | 0.81 | MAPT (0.58) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL314659 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL314657 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466806-A | Dyeing compositions containing 3-amino-4-nitroanisole derivatives and their use in dyeing keratin fibres as well as certain new said derivatives | L'OREAL (FR) | 1984-08-21 | — | — | US | claimed |
| US-5186717-A | Colorfastness, hair dyes | L'OREAL (FR) | 1993-02-16 | — | — | US | disclosed |
| US-5085666-A | NITROANILINES AND HAIR-DYEING COMPOSITIONS IN WHICH THEY ARE PRESENT | L'OREAL (FR) | 1992-02-04 | — | — | US | disclosed |
| US-5026401-A | Hair dyes | L'OREAL (FR) | 1991-06-25 | — | — | US | disclosed |
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4973757-A | Process for the preparation of nitroanilines | L'OREAL (FR) | 1990-11-27 | — | — | US | disclosed |
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |
| US-4466806-A | Dyeing compositions containing 3-amino-4-nitroanisole derivatives and their use in dyeing keratin fibres as well as certain new said derivatives | L'OREAL (FR) | 1984-08-21 | — | — | US | disclosed |
| US-4419101-A | Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres | L'OREAL (FR) | 1983-12-06 | — | — | US | disclosed |