Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9759792 | 0.99 | SMN1; SMN2 (0.50) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL9499752 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL11049649 | 0.86 | MAPT (0.59) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL21315653 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL29961863 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL111539 | 0.80 | KAT2B (0.59) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL29392855 | 0.80 | KAT2B (0.59) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL314657 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL314658 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL314659 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2AKR1B10AKR1B1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026401-A | Hair dyes | L'OREAL (FR) | 1991-06-25 | — | — | US | disclosed |