Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518433 | 0.87 | CYP19A1 (0.49) | SMN1; SMN2ADRB3CYP3A4LMNAL3MBTL1 | |
| SCHEMBL13765633 | 0.84 | TRPA1 (0.61) | TRPA1SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL2425719 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29725500 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28731430 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14762091 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2KCNA5CFTRSLC6A2SLC6A4 | |
| SCHEMBL2422449 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10589633 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2KCNA5ADRB3CFTRSLC6A2 | |
| SCHEMBL9743874 | 0.74 | CYP1A2 (0.50) | SMN1; SMN2KCNA5CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2422674 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400344-B1 | Pyridine derivatives and their use as fungicides | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| US-5266579-A | Controlling phytopathogens | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| US-5112828-A | Horticulture, agriculture | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0400344-A1 | Pyridine derivatives and their use as fungicides | BASF Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | disclosed |