Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363672 | 0.91 | KMT2A (0.46) | SMN1; SMN2KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL9363851 | 0.86 | MAPT (0.52) | KMT2ALMNANPSR1L3MBTL1MAPT | |
| SCHEMBL9502880 | 0.86 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9501420 | 0.82 | SLC22A12 (0.56) | SMN1; SMN2NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9499874 | 0.82 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9500262 | 0.82 | HIF1A (0.43) | SMN1; SMN2KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL9363653 | 0.81 | MAPT (0.50) | KMT2ALMNANPSR1L3MBTL1MAPT | |
| SCHEMBL9503090 | 0.79 | SLC22A12 (0.43) | SMN1; SMN2NPC1RAB9AHIF1ASLC22A12 | |
| SCHEMBL9363840 | 0.79 | ERAP1 (0.44) | KMT2ALMNANPSR1L3MBTL1MAPT | |
| SCHEMBL9363798 | 0.78 | EPHX2 (0.46) | SMN1; SMN2NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |