Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363798 | 0.92 | EPHX2 (0.46) | NPC1RAB9ASMN1; SMN2RORCEPHX2 | |
| SCHEMBL9363433 | 0.87 | RORC (0.46) | RORCPPARGTP53BRPF1HDAC1 | |
| SCHEMBL9500286 | 0.86 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9503090 | 0.82 | SLC22A12 (0.43) | NPC1RAB9ASMN1; SMN2RORCPOLB | |
| SCHEMBL9363762 | 0.81 | RORC (0.44) | RORCEPHX2 | |
| SCHEMBL9368608 | 0.80 | VNN1 (0.49) | NPC1RORCTP53HDAC1ALDH1A1 | |
| SCHEMBL9501041 | 0.79 | RORC (0.47) | RAB9ARORCTP53BRPF1HDAC1 | |
| SCHEMBL9363672 | 0.78 | KMT2A (0.46) | SMN1; SMN2EPHX2TP53ALDH1A1LMNA | |
| SCHEMBL9501420 | 0.77 | SLC22A12 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9363793 | 0.77 | RORC (0.46) | RORCHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |