Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512416 | 0.97 | ACACB (0.38) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9498182 | 0.96 | RAB9A (0.38) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9499663 | 0.95 | RAB9A (0.41) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9495912 | 0.94 | RAB9A (0.45) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9498130 | 0.94 | ACACB (0.38) | ACACBRAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9497021 | 0.93 | RAB9A (0.44) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9498310 | 0.93 | RAB9A (0.44) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9496009 | 0.92 | RAB9A (0.43) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9496652 | 0.92 | RAB9A (0.40) | ACACBRAB9AMAPTL3MBTL1CASP3 | |
| SCHEMBL9496215 | 0.92 | RAB9A (0.38) | ACACBRAB9AMAPTL3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-B1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |