Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | FPR3 | P25089 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697959 | 0.87 | ADRB2 (0.75) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL9499793 | 0.86 | ADRB2 (0.74) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL28044430 | 0.85 | ADRB2 (0.85) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL10697732 | 0.83 | ADRB2 (0.79) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| Bromide SCHEMBL10699615 | 0.82 | ADRB2 (0.75) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL10697568 | 0.82 | ADRB2 (0.80) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL30142619 | 0.81 | ADRB2 (0.79) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL9499929 | 0.81 | ADRB2 (0.77) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL4454918 | 0.81 | ADRB2 (0.96) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL14017126 | 0.81 | ADRB2 (0.96) | ADRB2ADRB1ADRB3SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317206-B1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |