Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930943 | 0.77 | DEPTOR (0.50) | POLBCES2CES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10926708 | 0.74 | DEPTOR (0.47) | POLBCES2CES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10930668 | 0.74 | ADRA2C (0.45) | POLBCES2CES1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11122024 | 0.72 | POLB (0.56) | POLBCYP3A4CYP2C9CES2CES1 | |
| Acetic Acid SCHEMBL11263006 | 0.71 | POLB (0.47) | POLBCYP3A4CYP2C9CES2CES1 | |
| Acetic Acid SCHEMBL11270809 | 0.71 | POLB (0.47) | POLBCYP3A4CYP2C9CES2CES1 | |
| SCHEMBL3280418 | 0.71 | POLB (0.55) | POLBCYP3A4CYP2C9CES2CES1 | |
| SCHEMBL6499020 | 0.71 | POLB (0.55) | POLBCYP3A4CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL684868 | 0.70 | KMT2A (0.52) | POLBCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL418096 | 0.69 | POLB (0.53) | POLBCYP3A4CYP2C9CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237099-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | disclosed |