Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496954 | 0.93 | MAPT (0.47) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL9775363 | 0.89 | PARP15 (0.48) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL9495514 | 0.81 | SRD5A2 (0.55) | CA1CA2KMT2ATSHR | |
| SCHEMBL69218 | 0.80 | CA1 (0.75) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL9731450 | 0.78 | CA1 (0.67) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL9549836 | 0.76 | CA1 (0.58) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL9496161 | 0.75 | KMT2A (0.54) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL21288599 | 0.75 | KMT2A (0.64) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL20252722 | 0.74 | CA1 (0.67) | CA1CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL2188276 | 0.74 | CA1 (0.88) | CA1CA2MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |