Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516221 | 0.80 | KMT2A (0.73) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL31403412 | 0.77 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14384682 | 0.76 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18103151 | 0.76 | ALDH1A1 (0.68) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18826484 | 0.75 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9500742 | 0.75 | CA1 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14384396 | 0.74 | MTNR1A (0.76) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL171438 | 0.74 | HPGD (0.71) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL14192610 | 0.74 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5612841 | 0.74 | TDP1 (0.77) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |