Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947564 | 0.89 | CHRM2 (0.45) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL949180 | 0.82 | F10 (0.49) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL948780 | 0.81 | ACHE (0.43) | CHRM2CHRM3F2F10CCR5 | |
| SCHEMBL949948 | 0.80 | F10 (0.36) | SMN1; SMN2F2F10 | |
| SCHEMBL949174 | 0.80 | CHRM2 (0.49) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL948506 | 0.78 | CHRM3 (0.42) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL949320 | 0.77 | CHRM3 (0.41) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL947325 | 0.76 | CHRM2 (0.40) | SMN1; SMN2CHRM2CHRM3CCR5ALDH1A1 | |
| SCHEMBL949956 | 0.75 | CHRM3 (0.48) | RECQLSMN1; SMN2CHRM2CHRM3F2 | |
| SCHEMBL949045 | 0.71 | F10 (0.77) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | RECQL 3956/4885SMN1; SMN2 3368/4885CHRM2 576/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | RECQL 3633/4885SMN1; SMN2 3635/4885CHRM2 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.