Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL9500922 | 1.00 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL27397102 | 0.91 | SLC7A5 (0.69) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL9780166 | 0.88 | SLC7A5 (0.59) | SLC7A5PTGS1ALPIPKMXIAP | |
| Iodofalan SCHEMBL8498125 | 0.88 | SLC7A5 (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL9636548 | 0.86 | SLC7A5 (0.67) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1908048 | 0.83 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL28900255 | 0.83 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL5699043 | 0.83 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL133206 | 0.83 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1908049 | 0.83 | SLC7A5 (0.89) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066103-A1 | Process for the reduction of reducible groups, and its application | Eckert, Heiner, dr. (DE) | 1982-12-08 | — | — | EP | claimed |
| EP-0347820-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PREPARATION AND APPLICATION OF THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5061787-A | IMMUNOSUPPRESSANTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0347820-A1 | Novel spergualin-related compounds and preparation and application of the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | disclosed |