SCHEMBL9500928

SCHEMBL9500928

CCOc1ccccc1NC(=O)C(=O)NN

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.65
LMNA P02545 2/20 0.59
MCL1 Q07820 1/20 0.59
KMT2A Q03164 4/20 0.58
CYP2C19 P33261 1/20 0.58
KDM4E B2RXH2 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
POLB P06746 2/20 0.56
KCNH2 Q12809 1/20 0.55
ALDH1A1 P00352 3/20 0.55
TSHR P16473 2/20 0.55
MEN1 O00255 2/20 0.55
NPC1 O15118 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
EGFR P00533 1/20 0.55
HPGD P15428 1/20 0.54
PTK2 Q05397 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8110954 0.92 GAA (0.75) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL10520727 0.86 GAA (0.63) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL29612239 0.86 GAA (0.67) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL744526 0.86 GAA (0.67) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL14224949 0.84 NPC1 (0.66) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL29365765 0.84 GAA (0.65) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL31442935 0.84 GAA (0.65) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL820418 0.84 GAA (0.65) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL453995 0.84 GAA (0.65) GAALMNAMCL1KMT2ACYP2C19
SCHEMBL30612660 0.84 GAA (0.65) GAALMNAMCL1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed