Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A9 | P48067 | 11/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233689 | 0.95 | SLC6A9 (0.71) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL27297187 | 0.89 | SLC6A9 (0.58) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL5142654 | 0.85 | SLC6A9 (0.68) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7307609 | 0.84 | SLC6A9 (0.69) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL9501066 | 0.84 | SLC6A4 (0.61) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL11350914 | 0.82 | SLC6A4 (0.57) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7308452 | 0.81 | KDM4E (0.61) | SLC6A9SLC6A4HRH3 | |
| Phosphoric Acid SCHEMBL10588440 | 0.81 | SLC6A4 (0.55) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7317614 | 0.81 | SLC6A4 (0.88) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL7158810 | 0.80 | SLC6A4 (0.73) | SLC6A9SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238959-A | For inhibiting serotonin uptake, antidepressant, suppression of alcoholism and obesity | ELI LILLY AND COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0336753-B1 | IMPROVEMENTS IN OR RELATING TO PROPANAMINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1992-07-08 | — | — | EP | disclosed |