Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993599 | 0.84 | TSHR (0.50) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL16993597 | 0.84 | TSHR (0.50) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL27861590 | 0.82 | TSHR (0.47) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL5081573 | 0.82 | TSHR (0.47) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL22714781 | 0.81 | ALDH1A1 (0.47) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL29631212 | 0.81 | ALDH1A1 (0.47) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL9500846 | 0.79 | TSHR (0.45) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL9712000 | 0.78 | TSHR (0.58) | TSHRALOX15ALDH1A1CA1CA2 | |
| SCHEMBL9657615 | 0.78 | ALDH1A1 (0.45) | TSHRPOLBALOX15ALDH1A1CYP1A2 | |
| SCHEMBL1497989 | 0.77 | TSHR (0.60) | TSHRPOLBALOX15ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |