Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311861 | 0.80 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL9419944 | 0.80 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL20787955 | 0.77 | TSHR (0.76) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10703473 | 0.74 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28068770 | 0.73 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL2146545 | 0.72 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL5833833 | 0.72 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ether SCHEMBL15941530 | 0.72 | TSHR (0.85) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27608864 | 0.72 | TSHR (0.85) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL1091906 | 0.71 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296890-B1 | HOSES | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5158113-A | Heavy-duty hose having a multi-layered core tube | THE YOKOHAMA RUBBER CO., LTD. | 1992-10-27 | — | — | US | disclosed |
| EP-0296890-A2 | Hoses | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |