Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16106125 | 0.89 | LMNA (0.42) | LMNAPTPN1MEN1KMT2AACACB | |
| SCHEMBL29471756 | 0.87 | LMNA (0.46) | LMNABLMPTPN1MEN1KMT2A | |
| SCHEMBL20680751 | 0.87 | LMNA (0.46) | LMNABLMPTPN1MEN1KMT2A | |
| SCHEMBL7880857 | 0.87 | ACACB (0.41) | LMNAPTPN1MEN1KMT2AACACB | |
| SCHEMBL5147248 | 0.86 | ACE2 (0.43) | LMNAACE2PTPN1MEN1KMT2A | |
| SCHEMBL4821885 | 0.85 | LMNA (0.70) | LMNABLMACE2PTPN1MEN1 | |
| SCHEMBL11308649 | 0.85 | LMNA (0.48) | LMNABLMPTPN1ACACBACACA | |
| SCHEMBL12960699 | 0.85 | LMNA (0.70) | LMNABLMACE2PTPN1MEN1 | |
| SCHEMBL29273105 | 0.85 | PTPN1 (0.43) | LMNAPTPN1ACACBACACAPSMD14 | |
| SCHEMBL9060842 | 0.85 | LMNA (0.70) | LMNABLMACE2PTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219733-A | Reacting sterol or fatty alcohol with fatty acid or ester in contact with microorganism-derived lipase in water or mixture of water and organic solvent | YOSHIKAWA OIL & FAT CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0195311-B1 | PROCESS FOR PREPARING FATTY ACID ESTERS | NIPPON FINE CHEMICAL CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |