Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25069357 | 1.00 | NPSR1 (0.40) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5504512 | 0.91 | MAPT (0.40) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9584777 | 0.91 | MAPT (0.40) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL5504513 | 0.91 | MAPT (0.40) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL25069597 | 0.87 | ESR1 (0.33) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8927291 | 0.86 | ALDH1A1 (0.38) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8927289 | 0.86 | NPSR1 (0.38) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8927294 | 0.86 | ALDH1A1 (0.38) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8927287 | 0.86 | NPSR1 (0.38) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7173250 | 0.86 | NPSR1 (0.43) | NPSR1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |