SCHEMBL9501186

SCHEMBL9501186

COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC(=O)c1c(Cl)ccc(S(=O)(=O)NCC(=O)O)c1Cl)C2=O

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440951 0.90 ELANE (0.67) ELANE
SCHEMBL7434713 0.85 ELANE (1.00) ELANE
SCHEMBL7437415 0.84 ELANE (1.00) ELANE
SCHEMBL7288209 0.83 ELANE (0.80) ELANE
SCHEMBL7434006 0.83 ELANE (1.00) ELANE
SCHEMBL7434313 0.81 ELANE (1.00) ELANE
SCHEMBL7430494 0.78 ELANE (0.82) ELANE
SCHEMBL7443983 0.77 ELANE (0.76) ELANE
SCHEMBL7429604 0.76 ELANE (0.77) ELANE
SCHEMBL7437318 0.76 ELANE (0.75) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250696-A Treatment of degenerative diseases STERLING WINTHROP INC. (US) 1993-10-05 US disclosed