Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874585 | 1.00 | CA1 (0.36) | CA1CA2LMNATSHRNFKB1 | |
| SCHEMBL2270668 | 0.85 | CES2 (0.48) | TSHR | |
| SCHEMBL9333592 | 0.85 | TSHR (0.32) | TSHR | |
| SCHEMBL5417762 | 0.85 | CES2 (0.48) | TSHR | |
| SCHEMBL2585370 | 0.85 | CES2 (0.48) | TSHR | |
| SCHEMBL10503205 | 0.85 | CES2 (0.48) | TSHR | |
| SCHEMBL2888223 | 0.85 | — | — | |
| SCHEMBL9417603 | 0.85 | CES2 (0.48) | TSHR | |
| SCHEMBL4525184 | 0.83 | TSHR (0.63) | LMNATSHRNFKB1PMP22 | |
| SCHEMBL4533145 | 0.83 | TSHR (0.63) | LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300849-B1 | PROCESS FOR THE CHEMICAL MODIFICATION OF PROTIDES, AND PRODUCTS SO MODIFIED | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-06-16 | — | — | EP | disclosed |
| EP-0300849-A1 | Process for the chemical modification of protides, and products so modified | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1989-01-25 | — | — | EP | disclosed |
| EP-0199644-A1 | Enzyme immobilisation | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-10-29 | — | — | EP | disclosed |