Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330173 | 0.87 | SOAT1 (0.46) | SOAT1KMT2A | |
| SCHEMBL9499589 | 0.86 | SOAT1 (0.51) | SOAT1LMNAKMT2ASMN1; SMN2LPAR1 | |
| SCHEMBL9091742 | 0.82 | MAPK1 (0.53) | SOAT1L3MBTL1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8838603 | 0.79 | MAPK1 (0.49) | SOAT1L3MBTL1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9092893 | 0.79 | KMT2A (0.47) | SOAT1L3MBTL1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8620559 | 0.77 | LPAR1 (0.44) | SOAT1LPAR1 | |
| SCHEMBL8613749 | 0.77 | LPAR1 (0.45) | SOAT1LPAR1 | |
| SCHEMBL8615128 | 0.75 | LPAR1 (0.48) | SOAT1LPAR1 | |
| SCHEMBL9093729 | 0.75 | SMN1; SMN2 (0.49) | SOAT1L3MBTL1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8117924 | 0.74 | MAPK1 (0.47) | SOAT1L3MBTL1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | claimed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5030653-A | N-2,6-dialkyl- or n-2,6-dialkoxyphenyl-n-arylalkylurea compounds | WARNER-LAMBERT COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| US-4948806-A | N-2,6-DIALKYL-OR N-2,6-DIALKOXYPHENYL-N'-ARYLALKYLUREA | WARNER-LAMBERT COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| US-4868210-A | PHENYL UREAS AND PHENYL THIOUREAS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |