Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620559 | 0.90 | LPAR1 (0.44) | LPAR1SOAT1TBXAS1 | |
| SCHEMBL9330173 | 0.89 | SOAT1 (0.46) | SOAT1 | |
| SCHEMBL8615128 | 0.87 | LPAR1 (0.48) | LPAR1SOAT1 | |
| SCHEMBL8615719 | 0.85 | TBXAS1 (0.41) | CCR5TBXA2RTBXAS1 | |
| SCHEMBL8618222 | 0.84 | SOAT1 (0.40) | LPAR1SOAT1 | |
| Hydrochloric Acid SCHEMBL8619453 | 0.84 | SOAT1 (0.39) | LPAR1SOAT1 | |
| SCHEMBL8797482 | 0.83 | LPAR1 (0.45) | LPAR1SOAT1TBXA2R | |
| SCHEMBL8616314 | 0.83 | TBXA2R (0.39) | TBXA2RTBXAS1 | |
| SCHEMBL8618649 | 0.82 | SOAT1 (0.39) | LPAR1SOAT1 | |
| SCHEMBL8618759 | 0.82 | TBXA2R (0.40) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-B1 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1998-05-06 | — | — | EP | claimed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | claimed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |