Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160680 | 1.00 | TSHR (0.40) | TSHRALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL6160683 | 1.00 | TSHR (0.40) | TSHRALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL7057550 | 0.98 | TSHR (0.38) | TSHRALDH1A1HPGDLTA4HMEN1 | |
| SCHEMBL28894182 | 0.94 | LTA4H (0.36) | TSHRHPGDLTA4HMEN1KMT2A | |
| SCHEMBL11699138 | 0.92 | LTA4H (0.37) | TSHRHPGDLTA4HMEN1KMT2A | |
| SCHEMBL9499471 | 0.92 | LTA4H (0.35) | TSHRALDH1A1HPGDMAPK1RECQL | |
| SCHEMBL11124801 | 0.91 | LTA4H (0.39) | TSHRHPGDLTA4HMEN1KMT2A | |
| SCHEMBL10798480 | 0.91 | LTA4H (0.39) | TSHRHPGDLTA4HMEN1KMT2A | |
| SCHEMBL10941285 | 0.90 | CYP1A2 (0.34) | TSHRALDH1A1HPGDMAPK1HRH3 | |
| SCHEMBL10941293 | 0.90 | CYP1A2 (0.34) | TSHRALDH1A1HPGDMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |