Phenyl Dihydrogen Phosphate

Phenyl Dihydrogen Phosphate

SCHEMBL9501417

O=P(O)(O)O.O=P(O)(O)Oc1ccccc1

nearest known ligand 0.95

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phenyl Dihydrogen Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.95
INPPL1 O15357 3/20 0.56
INPP5A Q14642 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
KDM4E B2RXH2 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
PDE3A Q14432 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
BLM P54132 1/20 0.48
ANPEP P15144 2/20 0.47
LAP3 P28838 2/20 0.47
INPP5B P32019 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Dihydrogen Phosphate SCHEMBL20263 0.97 SRC (1.00) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL28311333 0.97 SRC (1.00) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL9341481 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL8464887 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL8464886 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL25289578 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL9065420 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL4381495 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL187840 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1
Phenyl Dihydrogen Phosphate SCHEMBL23581620 0.95 SRC (0.95) SRCINPPL1INPP5AL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106632461-B A kind of preparation method of resorcinol tetraphenyldiphosphate 上海普信高分子材料有限公司 2018-05-08 CN claimed
CN-106632461-A Preparation method of tetraphenyl resorcinol bis(diphenylphosphate) 衢州普信新材料有限公司 2017-05-10 CN claimed
CN-106604949-A Alkoxy polycarbonates, bisphenol monomers, and methods of making and using the same 沙特基础工业全球技术公司 2017-04-26 CN claimed
CN-1214097-C Method for treating or pretreating containers CHEMETALL GMBH (DE) 2005-08-10 CN claimed
CN-1444642-A Method for treating or pretreating containers CHEMETALL GMBH (DE) 2003-09-24 CN claimed
CN-110225814-A Compositions for selective laser sintering and other additive manufacturing processes 沙特基础工业全球技术公司 2019-09-10 CN disclosed
CN-109863197-A Dynamic crosslinking network comprising non-networkization fire retardant 沙特基础工业全球技术公司 2019-06-07 CN disclosed
CN-109312152-A halogen-free flame-retardant resin composition 株式会社LG化学 2019-02-05 CN disclosed
CN-109196048-A The copolycarbonate composition of optical property with enhancing, the product formed by it and manufacturing method 沙特基础工业全球技术有限公司 2019-01-11 CN disclosed
CN-107614611-A Polycarbonate resin composition and preform made of polycarbonate resin 三菱瓦斯化学株式会社 2018-01-19 CN disclosed
CN-107216737-A Environment-friendly fireproof coating for equipment and preparation method thereof 合肥尚强电气科技有限公司 2017-09-29 CN disclosed
CN-106632461-A Preparation method of tetraphenyl resorcinol bis(diphenylphosphate) 衢州普信新材料有限公司 2017-05-10 CN disclosed
CN-103554864-B Releasing agent for transparent polyimide blends 沙特基础全球技术有限公司 2016-11-23 CN disclosed
CN-103732652-B Polysulfone compositions and its manufacture method and its application 沙特基础全球技术有限公司 2016-10-05 CN disclosed
CN-105885358-A Halogen-free high temperature resistant resin 西安超码复合材料有限公司 2016-08-24 CN disclosed
CN-103732652-A Polysulfone compositions and methods for the manufacture and use thereof SABIC INNOVATIVE PLASTICS IP 2014-04-16 CN disclosed
CN-1214097-C Method for treating or pretreating containers CHEMETALL GMBH (DE) 2005-08-10 CN disclosed
CN-1444642-A Method for treating or pretreating containers CHEMETALL GMBH (DE) 2003-09-24 CN disclosed
CN-1206027-A Thermoplastic resin composition DAICEL CHEM (JP) 1999-01-27 CN disclosed
US-5206404-A Purifying by passing through thin film evaporators; oxidation, wear, heat, hydroytic stability FMC CORPORATION (US) 1993-04-27 US disclosed