Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505512 | 0.90 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1 | |
| SCHEMBL9503586 | 0.85 | CYSLTR2 (0.79) | CYSLTR2CYSLTR1 | |
| SCHEMBL9501760 | 0.83 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1FAAHDAGLACES1 | |
| SCHEMBL9561419 | 0.79 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561482 | 0.79 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1 | |
| SCHEMBL9502587 | 0.75 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1DAGLA | |
| SCHEMBL9503345 | 0.75 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1FAAHDAGLA | |
| SCHEMBL10435616 | 0.74 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 | |
| SCHEMBL9505459 | 0.73 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1DAGLA | |
| SCHEMBL9155567 | 0.73 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |