Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.71 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504617 | 0.89 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1MAPTRXFP1DAGLA | |
| SCHEMBL9503364 | 0.89 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL125952 | 0.83 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL6437479 | 0.83 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL29473536 | 0.83 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9505512 | 0.83 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1MAPTRXFP1TBXAS1 | |
| Pobilukast SCHEMBL9508139 | 0.82 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL9508133 | 0.82 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9501760 | 0.82 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1DAGLA | |
| SCHEMBL9503341 | 0.80 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPTRXFP1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |