Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363290 | 0.86 | CYP3A4 (0.63) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL7753277 | 0.85 | CYP3A4 (0.54) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL1040127 | 0.84 | KMT2A (0.62) | CYP3A4MEN1KMT2ALMNANPSR1 | |
| SCHEMBL4267736 | 0.83 | MEN1 (0.76) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL20425429 | 0.83 | CYP3A4 (0.52) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL13461312 | 0.82 | CYP3A4 (0.50) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL1546422 | 0.81 | KMT2A (0.59) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL13292720 | 0.80 | PRSS1 (0.51) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL30473277 | 0.80 | PRSS1 (0.51) | MAOBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL6207157 | 0.80 | MAOA (0.57) | CYP3A4PBRM1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356681-B1 | DISAZO DYES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0356681-A1 | Disazo dyes | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |