Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24412648 | 0.88 | DNM1 (0.65) | DNM1NAAACASP2PAOXTSHR | |
| SCHEMBL4577306 | 0.88 | DNM1 (0.55) | DNM1NAAACNR1PAOXMEN1 | |
| SCHEMBL1527147 | 0.85 | DNM1 (0.72) | DNM1NAAACASP2PAOXTSHR | |
| SCHEMBL14907185 | 0.84 | DNM1 (0.71) | DNM1NAAACNR1CASP2MEN1 | |
| SCHEMBL8956620 | 0.84 | DNM1 (0.56) | DNM1NAAACASP2PAOXTSHR | |
| SCHEMBL8773743 | 0.83 | DNM1 (0.76) | DNM1NAAACASP2PAOXTSHR | |
| SCHEMBL23899001 | 0.83 | DNM1 (0.82) | DNM1NAAACASP2PAOXTSHR | |
| SCHEMBL12344052 | 0.82 | DNM1 (0.74) | DNM1NAAACASP2MEN1KMT2A | |
| SCHEMBL9498400 | 0.82 | DNM1 (0.71) | DNM1NAAACNR1PAOXMEN1 | |
| SCHEMBL7137887 | 0.82 | DNM1 (0.79) | DNM1NAAAPAOXTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |