SCHEMBL9501577

SCHEMBL9501577

C=CCO/C=C(\C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1234336 1.00 TSHR (0.32) TSHRGAAALDH1A1CYP3A4TDP1
Glycerin SCHEMBL18918228 0.88 CA1 (0.30) ALDH1A1
Methacrylic Acid SCHEMBL3688393 0.83
SCHEMBL22042685 0.83 MEN1 (0.35) TSHRALDH1A1TDP1
SCHEMBL562399 0.80 PTGS1 (0.30)
SCHEMBL8014309 0.79 TSHR (0.38) TSHRALDH1A1CYP3A4TDP1
SCHEMBL563601 0.77
SCHEMBL10325546 0.77 CYP3A4 (0.36) TSHRALDH1A1CYP3A4TDP1
SCHEMBL11385818 0.77 CYP3A4 (0.32) TSHRCYP3A4
SCHEMBL30655861 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116294-A1 ONE TERMINAL METHACRYLIC-MODIFIED ORGANO(POLY)SILOXANE HAVING POLY(ALKYLENE OXIDE) AT ω-TERMINAL, AND METHOD FOR PRODUCING SAME 信越化学工業株式会社 2020-06-11 WO disclosed
WO-2018160373-A1 DUAL CURE POLYORGANOSILOXANE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE DOW SILICONES CORPORATION (US) 2018-09-07 WO disclosed
EP-0292262-B1 COATING COMPOSITION KANSEI PAINT CO., LTD. (JP) 1993-04-07 EP disclosed
EP-0292262-A2 Coating composition KANSEI PAINT CO., LTD. (JP) 1988-11-23 EP disclosed
US-4329266-A PARTIALLY NEUTRALIZED CARBOXYLIC-CONTAINING ACRYLIC COPOLYMER MODIFIED BY AN UNSATURATED GLYCIDYL COMPOUND; WATERBASE PAINTS KANSAI PAINT CO., LTD. (JP) 1982-05-11 US disclosed