Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.32 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.32 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006159 | 0.89 | GLO1 (0.41) | TSHRMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL5152032 | 0.85 | TSHR (0.37) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6272798 | 0.81 | TSHR (0.49) | TSHRALDH1A1 | |
| SCHEMBL9241885 | 0.81 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL45287 | 0.81 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL524629 | 0.81 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL4564777 | 0.80 | LMNA (0.33) | TSHRCYP3A4TDP1MAPTALDH1A1 | |
| SCHEMBL180854 | 0.80 | LMNA (0.36) | TSHRCYP3A4MAPTALDH1A1MEN1 | |
| SCHEMBL11576487 | 0.79 | MAPT (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL9501577 | 0.79 | TSHR (0.32) | TSHRCYP3A4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711780-B1 | Process for the preparation of liquid crystalline polyorganosiloxanes containing (meth-)acryloxy groups | CONSORTIUM ELEKTROCHEM IND (DE) | 2000-01-05 | — | — | EP | disclosed |
| US-5641850-A | HYDROSILATION OF A HYDRIDOPOLYSILOXANE BY AN ALKENE CONTAINING MESOGENIC GROUPS FOLLOWED BY REACTION WITH AN ALKENE CONTAINING A (METH)ACRYLOXY GROUP; CROSSLINKING; HAZE-FREE FILMS | CONSORTIUM FUR ELECTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0711780-A1 | Process for the preparation of liquid crystalline polyorganosiloxanes containing (meth-)acryloxy groups | Consortium für elektrochemische Industrie GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |